Infant Diarrhoea and Ayurveda

Shankar4

Bihar India, Email: dravinashshankar@gmail.com

cartilaginous osteoarthropathy.

thoroughly interrogated for clinical presentation, history of treatment and their result.

transfusion and advocation of HERINA drop.

loss of fluid and electrolyte and cost of therapy without any untoward effects.

Osteoarthropathy; Herbomineral

Introduction

Diarrhoea ,a biggest infant killer worldwide specially in developing countries like India, Nepal, Bangladesh and Shrilanka , where a child suffers on an average 3-6 episodes of diarrhea in first year of life claiming death rate of 20-60/thousand children annually [1, 2, 3, 4, 5]. Interaction between diarrheal disease and nutritional status are complex and synergistic and serious issues globally., as they affect thousands of millions of young children every year and causes >3 million death of children < 5yrs in spite of intensive filed based diagnosis and treatment ,1,2 usually 109 of every 1000 children dies before 5 yrs (Unicef report 2012) and 11% death is due to diarrhoea, present death rate of 38 per thousand in India to be achieved by 2015 ,though diarrheal death dropped in India Usually child lose water and electrolyte alike adult due to fairly large area of secreting intestinal mucosa [6, 7].

and morbidity in infants due to altered secretory and absorptive mechanism of intestinal mucosa, a clinical study to evaluate a herbo mineral anti-diarrheal composite HERINA in declining the secretion of intestinal mucosa and promotion of fluid and electrolyte transport in changing the consistency and frequency of stool and safety profile in infant diarrhoea is planned

Results

Among the selected infants ,majority (39%) were of age group 6-9 months and 17% were of age group 3-6 months. 32% infants had frequency of motion 4-6 every 24 hours while 19% shows >13 every 24 hours.

• (T-1). Out of all 65% (1136) infants present with lose watery motion 23% and 12% infants had greenish lose motion and lose motion with mucous and froth respectively, 85% had fever and 80% presented with scanty urine.
• (T-2)As per hydration status all are dehydrated but

41% and 39% were with severe and moderate dehydration respectively

• (T- 3) Stool examination of the infants shows absence of respective pathogens in 33% male and 34% female though 12% of both male and female show presence of Shigella and 16% of male and 15% female shows presence of Salmonella.
• (T- 4) No infants with history of fever show significant bacteriuria or positive Microstix -N test for Urinary tract infection.

Hematological status of majority infants was within normal limit or non-reveal haemoglobin deficiency or any haemato pathology. All infants taking HERINA drop shows earliest change in consistency and frequency of stool with complete normalization within 72 hours while others had deterioration of hydration status (39%) and needed intravenous fluid administration with advocation of HERINA drop. Crave for water in infants on HERINA drop ceased within 24 hours though some had within 12 hours while in others persisted for more than a week. 93% infants taking HERINA drop had grade I clinicopathological cure while others had worsening of

Discussion

In spite of enormous advancement in diarrhoeal management mortality and morbidity remain very common in infants due to acute diarrhoea [14, 15, 16, 17]. Present study reveals earliest decline in frequency and change in stool consistency, resulting in short duration of therapy and minimal .loss of fluid and electrolytes, checks need of intravenous fluid and electrolyte supplementation. Limitations of disease’s duration also check untoward effects as revealed by unaltered haematological, hepatic and renal function. Early change in consistency and decline in frequency of lose motion and loss of fluid and electrolytes in infants taking loss of fluid and electrolytes, checks need of intravenous fluid and electrolyte supplementation. Not only this short duration of diseases check untoward effects as revealed by unaltered haematological, hepatic and renal function. Early change in consistency and decline in frequency of lose motion and loss of fluid and electrolytes in infants taking Herina drop can be explained as-Constituents of Herina drop inhibits intestinal enkephalin (a membrane bound metalo peptidase) and prolong the anti-secretory effect of encephalin resulting in reduced secretion of water and electrolyte in the intestinal lumen, ultimately declining the intestinal load and intestinal stretch receptor response, finally reduce stretch, stimulation of the intestinal musculature leading to decline in tenesmus and defecation response [18]. Without increasing intestinal transit time and promoting bacterial colonization or fluid pooling in the distended bowel lumen or causing constipation can be explained as-Active bio molecule of Herina drop constituents inhibits intestinal enkephalin (a membrane bound metalo peptidase) and prolong the anti- secretory effect of encephalin resulting in reduced secretion of water and electrolyte in the intestinal lumen, ultimately declining the intestinal load and intestinal stretch receptor response , finally reduce stretch ,stimulation of the intestinal musculature leading to decline in tenesmus and defecation response. Without increasing intestinal transit time and promoting bacterial colonization or fluid pooling in the distended bowel lumen or causing constipation

• Active constituents of the composite-Discourage further multiplication or proliferation of causative pathogen [18].
• Adsorb the toxin secreted by microbes, hence relieves toxin induced tenesmus with check on intestinal hyperperistalsis.
• Astringent action of the constituents also bio regulate gut motility.
• Digestive tonic action promote appetite hence rejuvenate lust of breast sucking.
• Desired dilution of the suspension provides adequate water, in addition to electrolytes provided by the constituent.

Conclusion

Diarrhoea in infants’ posses’ high risk and mortality. Prescription of antimicrobial and antiprotozoal preparation poses life threatening sequel as infants diarrhoea is usually viral or nonspecific or dentition diarrhoea caused due to altered enkephalin secretion and Sodium potassium ATPase pump activity, Thus herb mineral preparation which possess natural soothing agent, and Enkephalin bio regulator and promote pump activity bioregulation without any adversity securing ensured diarrhoea control .