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Medical Journal of Clinical Trials & Case Studies Research Article 4 min read

Axial Spondyloarthritis in Inflammatory Bowel Diseases

Hana S*, Asma B, Lamine H, Aida B, Rawdha T and Msaddak A
* Corresponding author
ISSN: 2578-4838  10.23880/mjccs-16000115  Received: October 13, 2017  Published: October 27, 2017
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Abstract

 Rheumatic manifestations are described in 25 to 30% of patients with IBD and represents the most frequent extra intestinal manifestation [1,2]. The association between ankylosing spondylitis and IBD was recognized as non-fortuitous since 1960 [3]. The frequency of axial spondyloarthritis (AS) is very variable [4]. This frequency depends to the study design with increased frequency in prospective studies.                                              

Editorial

Rheumatic manifestations are described in 25 to 30% of patients with IBD and represents the most frequent extra intestinal manifestation [1, 2]. The association between ankylosing spondylitis and IBD was recognized %: percentage; N: number of patients Table 1: Frequency of axial spondyloarthritis in literature. The frequency depends also on the imaging technique used. Indeed, it was between 3 and 11% if the X-Ray was used and about 30% if the CT scan was performed [5]. In the studies of Master et al. and Davis et al., a sacroiliitis has been found in 50% of cases in bone scintigraphy [6, 7]. Moreover, the frequency of AS depends on patient’s criteria selection. The AS was observed more frequently when European Spondylarthropathy Study Group (ESSG) criteria were used and less frequently when modified New York criteria were used [8, 9, 10, 11, 12, 13]. Regarding risk factor for AS, Saadallaoui Ben Hamida, et al. [12], found that age older than 35 years old is a risk factor for AS with a relative risk of 5.8. Several studies didn’t prove sex as risk factor [12, 14]. Correlation between smoking and rheumatic manifestations of IBD had been discussed with contradictory results [15]. The impact of intestinal disease on risk for AS showed different conclusions. Indeed, the intestinal extension had a positive impact in the study performed by Saadallaoui Ben Hamida, et al. [12] and no impact in the study performed by Mester, et al. [6]. The high disease activity was associated with higher frequency of rheumatic manifestations only with crohn disease [16]. Few studies had discussed the impact of therapeutics on occurring AS. Moreover, elevated inflammatory blood tests were not considered as predictive factors for AS [12].

Conclusion

We recommend systematic checking of AS by a clinical exam and systematic radiological assessment for all patients with IBD and long-term follow-up of patients to detect signs of AS.

References

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@article{hana2017,
  title   = {Axial Spondyloarthritis in Inflammatory Bowel Diseases},
  author  = {Hana S, Asma B, Lamine H, Aida B, Rawdha T and Msaddak A},
  journal = {Medical Journal of Clinical Trials & Case Studies},
  year    = {2017},
  volume  = {1},
  number  = {3},
  doi     = {10.23880/mjccs-16000115}
}
Hana S, Asma B, Lamine H, Aida B, Rawdha T and Msaddak A (2017). Axial Spondyloarthritis in Inflammatory Bowel Diseases. Medical Journal of Clinical Trials & Case Studies, 1(3). https://doi.org/10.23880/mjccs-16000115
TY  - JOUR
TI  - Axial Spondyloarthritis in Inflammatory Bowel Diseases
AU  - Hana S, Asma B, Lamine H, Aida B, Rawdha T and Msaddak A
JO  - Medical Journal of Clinical Trials & Case Studies
PY  - 2017
VL  - 1
IS  - 3
DO  - 10.23880/mjccs-16000115
ER  -