Abstract

Hypogonadotrophic hypogonadism, which is characterized by low serum testosterone co-existing with elevated Luteinizing hormone (LH) and Follicle stimulating hormone (FSH) has been reported to be a common finding in poorly managed diabetes mellitus (DM). This study is an attempt to investigate the impact of oral exogenous testosterone on the pattern of gonadal hormone profile in male Wistar rats, without any form of antidiabetic therapy.