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Nanomedicine & Nanotechnology Open Access Research Article 3 min read

Modern Nanomedicine & Nanobiotechnology in Maxillofaciale Surgery and Stomatology

Peredkov K Ya*
* Corresponding author
ISSN: 2574-187X  10.23880/nnoa-16000156  Received: December 25, 2018  Published: January 02, 2019
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Keywords
Modern Nanomedicine Nanobiotechnology Surgery Stomatology
Abstract

Nanomedicine-trend in modern medicine, based on the use of the unique capabilities of nanomaterials and nano-objects for the selection, design, and changes in biological systems on human low-molecular level.

Introduction

Nanotechnology- an interdisciplinary field of fundamental and applied science and technology, which consists of a combination of theoretical study and practical research methods, analysis and synthesis, as well as methods of production and application products with a given atomic structure by controlled manipulation of individual atoms and molecules (Figure 1) [1].

Figure 1
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Figure 1

Artificial bone (biocomposites), bioactive inorganic multiphase composite material (synthesized on the basis of nanocrystals gidroksilappatit, tricalcium- phosphate, bioactive glass, mixed oxides of metals and nonmetals), similar in composition to natural bone mineral and intended to restore it with different pathologies Figures 2 & 3.

Figure 2: packages bioceramics in shape gidroxilapatit, threecalciumphosphatis and bioactive glass.
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Figure 2: packages bioceramics in shape gidroxilapatit, threecalciumphosphatis and bioactive glass.
Figure 3: In the complement of biocomposit to be possibility to add antiseptic preparations.
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Figure 3: In the complement of biocomposit to be possibility to add antiseptic preparations.

System of artificial bone are multifunctional materials, as they have the ability to osseointegration, osteokonduktion, osteoinduktion, osteostimulyation and osteogenesis Figure 4 [2, 3].

After the occurrence of bone-ceramic complex in the body material is partially or completely resorbed at the planned time-from 1,5-2 months- to several years, being replaced by bone tissue, which consists of products of resorbtion and synthesis.

Mechanism, the nature and rate of resorbtion is planned and managed composition and structure of complex artificial bone.

Figure 4: Osteointegration plates in a bone with bioceramics сovering and without.
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Figure 4: Osteointegration plates in a bone with bioceramics сovering and without.
Figure 5: Application of bioceramics in the defects of different bones. Using of biocomposites in oral and maxillo-facial surgery is possible (Figure 6):
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Figure 5: Application of bioceramics in the defects of different bones. Using of biocomposites in oral and maxillo-facial surgery is possible (Figure 6):
Figure 6: Using of biocomposites in oral and maxillo-facial surgery.
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Figure 6: Using of biocomposites in oral and maxillo-facial surgery.
Figure 7: In oral surgery - treatment defect of alveolar process with bioceramics to successive implantation
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Figure 7: In oral surgery - treatment defect of alveolar process with bioceramics to successive implantation

After the occurrence of bone-ceramic complex in the body material is partially or completely resorbed at the planned time-from 1,5-2 months- to several years, being replaced by bone tissue, which consists of products of resorbtion and synthesis.

Mechanism, the nature and rate of resorbtion is planned and managed composition and structure of complex artificial bone.

Selection of nonrezorbtion of the complex, which firmly holds the specified shape and volume, such as alveolar jaw. Biocompozit contains only the highest biocompatibility of inorganic constituents, which do not cause abnormal immune reactions, and inorganic baktericidus supplements, preobstruction inflammatory complications.

Due to the absence of organic components is possible multisterilization of reusable material. The using of autologous bone-may be replaced and supplemented by using of modern bioactive ceramics with the planned biological properties (Figure 5).

Figure 8: sinus-lifting left maxilla sinus and treatment chronic sinusitis with anticeptic bioceramics Thus, modern biocomposites represent the latest concept in the development of bioactive inorganic materials for reconstruction of bone tissue.
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Figure 8: sinus-lifting left maxilla sinus and treatment chronic sinusitis with anticeptic bioceramics Thus, modern biocomposites represent the latest concept in the development of bioactive inorganic materials for reconstruction of bone tissue.
Figure 9
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Figure 9
Figure 10
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Figure 10

-To fill the bone cavities after capsulotomy and cystectomy, treatment of osteomyelitis. -To form the bone wall with perforated sinusitis. - For bone grafting in plastic surgery. -To fill bone defects. -For a sinus-lift. (Figure 8) -Аt chronic sinuitiss In stomatology (Figure 7)[4, 5, 6]: -For the filling of periodontal defects. -To fill the holes removed teeth. -When you atrophy of alveolar bone in the jaw bone for augmentation. -For obturating dentinal canals. -In a deep root canal fillings, including extraapix therapy.

Figure 11
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Figure 11
Figure 12
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Figure 12

References

  1. Drexler KE, Peterson C, Pergamit G, Brand S (1991) Unbundling the future: The nanotechnology revolution.
  2. Roco MC (2001) Inernational strategy for nanotechnology researsh and development. Journal of Nanoparticle Research 3(5-6): 353-360.
  3. Rybachuk AV, Rieznichenko LS, Dybkova SN, Gruzina T, Ulberg Z, et al. (2014) Prospects of using silver and gold nanoparticles in the prevention and treatment of purulent-inflammatory diseases of the maxillofacial area. Ukrainian scientific and medical youth magazine 4: 42-47.
  4. Rybachuk AV Silver nanoparticles and their combination with gold nanoparticles as new effective antimicrobial substances for maxillofacial surgery and dental implantology.
  5. Rieznichenko LS, Malanchuk VA (2015) E-MRS Spring Meeting 11-15 May 2015, Lille, France.Rieznichenko LS, Rybachuk AV, Bilous S (2016) Silver nanoparticles: synthesis, effectiveness in treatment of purulent inflammatory diseases of the maxillofacial area, development of dosage forms. Journal of Chemical and Pharmaceutical Research 8(1): 332- 338.
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@article{peredkov2019,
  title   = {Modern Nanomedicine & Nanobiotechnology in Maxillofaciale
Surgery and Stomatology},
  author  = {Peredkov K Ya},
  journal = {Nanomedicine & Nanotechnology Open Access},
  year    = {2019},
  volume  = {4},
  number  = {1},
  doi     = {10.23880/nnoa-16000156}
}
Peredkov K Ya (2019). Modern Nanomedicine & Nanobiotechnology in Maxillofaciale
Surgery and Stomatology. Nanomedicine & Nanotechnology Open Access, 4(1). https://doi.org/10.23880/nnoa-16000156
TY  - JOUR
TI  - Modern Nanomedicine & Nanobiotechnology in Maxillofaciale
Surgery and Stomatology
AU  - Peredkov K Ya
JO  - Nanomedicine & Nanotechnology Open Access
PY  - 2019
VL  - 4
IS  - 1
DO  - 10.23880/nnoa-16000156
ER  -